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2qst

From Proteopedia

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[[Image:2qst.png|left|200px]]
 
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{{STRUCTURE_2qst| PDB=2qst | SCENE= }}
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==Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)==
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<StructureSection load='2qst' size='340' side='right'caption='[[2qst]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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===Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QST FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18086185}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qst OCA], [https://pdbe.org/2qst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qst RCSB], [https://www.ebi.ac.uk/pdbsum/2qst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qst ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2qst]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/CEAM5_HUMAN CEAM5_HUMAN] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.<ref>PMID:10864933</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:018086185</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qst_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qst ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Korotkova, N.]]
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[[Category: Large Structures]]
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[[Category: Moseley, S L.]]
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[[Category: Korotkova N]]
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[[Category: Stenkamp, R E.]]
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[[Category: Le Trong I]]
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[[Category: Trong, I Le.]]
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[[Category: Moseley SL]]
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[[Category: Cell adhesion]]
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[[Category: Stenkamp RE]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Immunoglobulin domain]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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Current revision

Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)

PDB ID 2qst

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