3bgd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3bgd" [edit=sysop:move=sysop])
Current revision (09:28, 21 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3bgd.png|left|200px]]
 
-
{{STRUCTURE_3bgd| PDB=3bgd | SCENE= }}
+
==Thiopurine S-Methyltransferase==
-
 
+
<StructureSection load='3bgd' size='340' side='right'caption='[[3bgd]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
===Thiopurine S-Methyltransferase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3bgd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BGD FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18484748}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PM6:9H-PURINE-6-THIOL'>PM6</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bgd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bgd OCA], [https://pdbe.org/3bgd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bgd RCSB], [https://www.ebi.ac.uk/pdbsum/3bgd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bgd ProSAT]</span></td></tr>
-
[[3bgd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGD OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/TPMT_MOUSE TPMT_MOUSE] Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.
-
<ref group="xtra">PMID:018484748</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bg/3bgd_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bgd ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Thiopurine S-methyltransferase]]
+
[[Category: Peng Y]]
-
[[Category: Peng, Y.]]
+
[[Category: Yee VC]]
-
[[Category: Yee, V C.]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: S-adenosyl-l-methionine]]
+
-
[[Category: Transferase]]
+

Current revision

Thiopurine S-Methyltransferase

PDB ID 3bgd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3bgd"
Personal tools