3dkm

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[[Image:3dkm.png|left|200px]]
 
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{{STRUCTURE_3dkm| PDB=3dkm | SCENE= }}
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==Crystal structure of the HECTD1 CPH domain==
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<StructureSection load='3dkm' size='340' side='right'caption='[[3dkm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3dkm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DKM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dkm OCA], [https://pdbe.org/3dkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dkm RCSB], [https://www.ebi.ac.uk/pdbsum/3dkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dkm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/3dkm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dkm ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the HECTD1 CPH domain===
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==See Also==
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*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3dkm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKM OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bochkarev A]]
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[[Category: Dhe-Paganon, S.]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M.]]
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[[Category: Dhe-Paganon S]]
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[[Category: Li, Y.]]
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[[Category: Edwards AM]]
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[[Category: Qiu, L.]]
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[[Category: Li Y]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Qiu L]]
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[[Category: Walker, J R.]]
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[[Category: Walker JR]]
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[[Category: Wolkstrom, M.]]
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[[Category: Wolkstrom M]]
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[[Category: Ank repeat]]
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[[Category: Ligase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Ubl conjugation pathway]]
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Current revision

Crystal structure of the HECTD1 CPH domain

PDB ID 3dkm

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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