2q9q
From Proteopedia
(Difference between revisions)
m (Protected "2q9q" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2q9q.png|left|200px]] | ||
| - | + | ==The crystal structure of full length human GINS complex== | |
| - | + | <StructureSection load='2q9q' size='340' side='right'caption='[[2q9q]], [[Resolution|resolution]] 2.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2q9q]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.36Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9q OCA], [https://pdbe.org/2q9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9q RCSB], [https://www.ebi.ac.uk/pdbsum/2q9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9q ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2q9q]] is a 8 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PSF2_HUMAN PSF2_HUMAN] The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.<ref>PMID:17417653</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q9q_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q9q ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chang YP]] |
| - | [[Category: | + | [[Category: Chen XS]] |
| - | [[Category: | + | [[Category: Wang G]] |
| - | + | ||
| - | + | ||
Current revision
The crystal structure of full length human GINS complex
| |||||||||||
