2ywk

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[[Image:2ywk.png|left|200px]]
 
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{{STRUCTURE_2ywk| PDB=2ywk | SCENE= }}
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==Crystal structure of RRM-domain derived from human putative RNA-binding protein 11==
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<StructureSection load='2ywk' size='340' side='right'caption='[[2ywk]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
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===Crystal structure of RRM-domain derived from human putative RNA-binding protein 11===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ywk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YWK FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[2ywk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWK OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ywk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywk OCA], [https://pdbe.org/2ywk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ywk RCSB], [https://www.ebi.ac.uk/pdbsum/2ywk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ywk ProSAT], [https://www.topsan.org/Proteins/RSGI/2ywk TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RBM11_HUMAN RBM11_HUMAN] Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.<ref>PMID:21984414</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yw/2ywk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ywk ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kaminishi, T.]]
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[[Category: Large Structures]]
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[[Category: Kawazoe, M.]]
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[[Category: Kaminishi T]]
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[[Category: Morita, S.]]
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[[Category: Kawazoe M]]
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[[Category: Nishino, A.]]
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[[Category: Morita S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Nishino A]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu M]]
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[[Category: Takemoto, C.]]
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[[Category: Takemoto C]]
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[[Category: Terada, T.]]
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[[Category: Terada T]]
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[[Category: Uchikubo-Kamo, T.]]
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[[Category: Uchikubo-Kamo T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rna binding protein]]
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[[Category: Rna-binding]]
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[[Category: Rrm-domain]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of RRM-domain derived from human putative RNA-binding protein 11

PDB ID 2ywk

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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