2yz2
From Proteopedia
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| - | [[Image:2yz2.png|left|200px]] | ||
| - | + | ==Crystal structure of the ABC transporter in the cobalt transport system== | |
| - | + | <StructureSection load='2yz2' size='340' side='right'caption='[[2yz2]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2yz2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZ2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yz2 OCA], [https://pdbe.org/2yz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yz2 RCSB], [https://www.ebi.ac.uk/pdbsum/2yz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yz2 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yz2 TOPSAN]</span></td></tr> |
| - | [[2yz2]] is a 2 chain structure with sequence from [ | + | </table> |
| - | [ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/ECFA2_THEMA ECFA2_THEMA] ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.<ref>PMID:23359690</ref> |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yz2_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yz2 ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[ | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Thermotoga maritima MSB8]] |
| - | [[Category: | + | [[Category: Bessho Y]] |
| - | [[Category: | + | [[Category: Ethayathullah AS]] |
| - | [[Category: | + | [[Category: Kaur P]] |
| + | [[Category: Padmanabhan B]] | ||
| + | [[Category: Singh TP]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Crystal structure of the ABC transporter in the cobalt transport system
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