2wns

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[[Image:2wns.png|left|200px]]
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==HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)==
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<StructureSection load='2wns' size='340' side='right' caption='[[2wns]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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{{STRUCTURE_2wns| PDB=2wns | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNS FirstGlance]. <br>
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===HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgy|2jgy]], [[2v30|2v30]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wns OCA], [http://pdbe.org/2wns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wns RCSB], [http://www.ebi.ac.uk/pdbsum/2wns PDBsum]</span></td></tr>
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[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA].
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wns_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wns ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
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[[Category: Homo sapiens]]
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__TOC__
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</StructureSection>
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[[Category: Human]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson, A.]]
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[[Category: Johansson, A]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kotyenova, T.]]
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[[Category: Kotyenova, T]]
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[[Category: Kotzch, A.]]
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[[Category: Kotzch, A]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nielsen, T K.]]
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[[Category: Nielsen, T K]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: Roos, A.]]
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[[Category: Roos, A]]
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[[Category: Sagemark, J.]]
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[[Category: Sagemark, J]]
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[[Category: Schueler, H.]]
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[[Category: Schueler, H]]
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[[Category: Schutz, P.]]
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[[Category: Schutz, P]]
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[[Category: Siponen, M I.]]
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[[Category: Siponen, M I]]
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[[Category: Svensson, L.]]
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[[Category: Svensson, L]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L.]]
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[[Category: Tresaugues, L]]
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[[Category: Vandenberg, S.]]
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[[Category: Vandenberg, S]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M.]]
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[[Category: Welin, M]]
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[[Category: Wisniewska, M.]]
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[[Category: Wisniewska, M]]
[[Category: Decarboxylase]]
[[Category: Decarboxylase]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]

Current revision

HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)

2wns, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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