2vkn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2vkn" [edit=sysop:move=sysop])
Current revision (15:23, 13 December 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2vkn.png|left|200px]]
 
-
{{STRUCTURE_2vkn| PDB=2vkn | SCENE= }}
+
==YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2==
-
 
+
<StructureSection load='2vkn' size='340' side='right'caption='[[2vkn]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-
===YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2vkn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2qk6 2qk6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKN FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[2vkn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2qk6 2qk6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKN OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkn OCA], [https://pdbe.org/2vkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkn RCSB], [https://www.ebi.ac.uk/pdbsum/2vkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkn ProSAT]</span></td></tr>
-
[[Category: Mitogen-activated protein kinase kinase]]
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SHO1_YEAST SHO1_YEAST] Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane. PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures. Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress. Involved in the regulation of the mating pathway. May be a receptor that feeds into the pseudohyphal growth pathway.<ref>PMID:10762242</ref> <ref>PMID:10931333</ref> <ref>PMID:10970855</ref> <ref>PMID:10980703</ref> <ref>PMID:11084293</ref> <ref>PMID:11922108</ref> <ref>PMID:12455951</ref> <ref>PMID:12511654</ref> <ref>PMID:14595107</ref> <ref>PMID:15020407</ref> <ref>PMID:15200958</ref> <ref>PMID:15200959</ref> <ref>PMID:15256499</ref> <ref>PMID:16778768</ref> <ref>PMID:18480263</ref> <ref>PMID:19318625</ref> <ref>PMID:19439450</ref> <ref>PMID:7624781</ref> <ref>PMID:9180081</ref> <ref>PMID:9744864</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkn_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vkn ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Kursula, I.]]
+
[[Category: Kursula I]]
-
[[Category: Kursula, P.]]
+
[[Category: Kursula P]]
-
[[Category: Paraskevopoulos, K.]]
+
[[Category: Paraskevopoulos K]]
-
[[Category: Song, Y H.]]
+
[[Category: Song YH]]
-
[[Category: Wilmanns, M.]]
+
[[Category: Wilmanns M]]
-
[[Category: Membrane]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: S. cerevisiae]]
+
-
[[Category: Sh3 domain]]
+
-
[[Category: Transmembrane]]
+

Current revision

YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2

PDB ID 2vkn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2vkn"
Personal tools