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3bov

From Proteopedia

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[[Image:3bov.png|left|200px]]
 
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{{STRUCTURE_3bov| PDB=3bov | SCENE= }}
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==Crystal structure of the receptor binding domain of mouse PD-L2==
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<StructureSection load='3bov' size='340' side='right'caption='[[3bov]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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===Crystal structure of the receptor binding domain of mouse PD-L2===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3bov]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BOV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18641123}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bov OCA], [https://pdbe.org/3bov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bov RCSB], [https://www.ebi.ac.uk/pdbsum/3bov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bov ProSAT]</span></td></tr>
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[[3bov]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BOV OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PD1L2_MOUSE PD1L2_MOUSE] Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.<ref>PMID:11283156</ref> <ref>PMID:11224527</ref> <ref>PMID:12719480</ref>
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<ref group="xtra">PMID:018641123</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bov_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bov ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Cao, E.]]
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[[Category: Cao E]]
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[[Category: Lazar-Molnar, E.]]
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[[Category: Lazar-Molnar E]]
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[[Category: Nathenson, S G.]]
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[[Category: Nathenson SG]]
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[[Category: Ramagopal, U.]]
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[[Category: Ramagopal U]]
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[[Category: Toro, R.]]
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[[Category: Toro R]]
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[[Category: B7-dc]]
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[[Category: Glycoprotein]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin domain]]
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[[Category: Membrane]]
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[[Category: Pd-l2]]
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[[Category: Programmed death-1 ligand2]]
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[[Category: Receptor]]
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[[Category: Transmembrane]]
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Current revision

Crystal structure of the receptor binding domain of mouse PD-L2

PDB ID 3bov

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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