2qer
From Proteopedia
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- | [[Image:2qer.png|left|200px]] | ||
- | + | ==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro== | |
- | + | <StructureSection load='2qer' size='340' side='right'caption='[[2qer]], [[Resolution|resolution]] 2.17Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2qer]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QER FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> | |
- | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
- | [[2qer]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qer OCA], [https://pdbe.org/2qer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qer RCSB], [https://www.ebi.ac.uk/pdbsum/2qer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qer ProSAT]</span></td></tr> |
- | [ | + | </table> |
- | [[ | + | == Function == |
- | [[ | + | [https://www.uniprot.org/uniprot/A3FQ68_CRYPI A3FQ68_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223] |
- | [[ | + | == Evolutionary Conservation == |
- | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | [ | + | Check<jmol> |
- | [[ | + | <jmolCheckbox> |
- | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qe/2qer_consurf.spt"</scriptWhenChecked> |
- | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
- | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
- | [[Category: | + | </jmolCheckbox> |
- | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qer ConSurf]. |
- | [[Category: | + | <div style="clear:both"></div> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Cryptosporidium parvum Iowa II]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Amani M]] |
- | [[Category: | + | [[Category: Arrowsmith CH]] |
- | [[Category: | + | [[Category: Artz JD]] |
- | [[Category: | + | [[Category: Bochkarev A]] |
- | [[Category: | + | [[Category: Edwards AM]] |
- | [[Category: | + | [[Category: Hassanali A]] |
- | [[Category: | + | [[Category: Hills T]] |
- | [[Category: | + | [[Category: Hui R]] |
- | [[Category: | + | [[Category: Kozieradzki I]] |
- | [[Category: | + | [[Category: Lew J]] |
- | [[Category: | + | [[Category: Lin L]] |
+ | [[Category: Schapira M]] | ||
+ | [[Category: Sundstrom M]] | ||
+ | [[Category: Vedadi M]] | ||
+ | [[Category: Wasney G]] | ||
+ | [[Category: Weigelt J]] | ||
+ | [[Category: Wernimont AK]] | ||
+ | [[Category: Zhao Y]] |
Current revision
Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro
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Categories: Cryptosporidium parvum Iowa II | Large Structures | Amani M | Arrowsmith CH | Artz JD | Bochkarev A | Edwards AM | Hassanali A | Hills T | Hui R | Kozieradzki I | Lew J | Lin L | Schapira M | Sundstrom M | Vedadi M | Wasney G | Weigelt J | Wernimont AK | Zhao Y