2z84
From Proteopedia
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- | [[Image:2z84.png|left|200px]] | ||
- | + | ==Insights from crystal and solution structures of mouse UfSP1== | |
- | + | <StructureSection load='2z84' size='340' side='right'caption='[[2z84]], [[Resolution|resolution]] 1.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2z84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z84 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z84 OCA], [https://pdbe.org/2z84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z84 RCSB], [https://www.ebi.ac.uk/pdbsum/2z84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z84 ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[2z84]] is a 1 chain structure with sequence from [ | + | == Function == |
+ | [https://www.uniprot.org/uniprot/UFSP1_MOUSE UFSP1_MOUSE] Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.<ref>PMID:17182609</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z84_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z84 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
- | [[Category: Ahn | + | [[Category: Ahn HC]] |
- | [[Category: Chung | + | [[Category: Chung CH]] |
- | [[Category: Ha | + | [[Category: Ha BH]] |
- | [[Category: Kang | + | [[Category: Kang SH]] |
- | [[Category: Kim | + | [[Category: Kim EE]] |
- | [[Category: Tanaka | + | [[Category: Tanaka K]] |
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Current revision
Insights from crystal and solution structures of mouse UfSP1
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Categories: Large Structures | Mus musculus | Ahn HC | Chung CH | Ha BH | Kang SH | Kim EE | Tanaka K