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3dkx

From Proteopedia

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[[Image:3dkx.png|left|200px]]
 
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{{STRUCTURE_3dkx| PDB=3dkx | SCENE= }}
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==Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), trigonal form, to 2.7 Ang resolution==
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<StructureSection load='3dkx' size='340' side='right'caption='[[3dkx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), trigonal form, to 2.7 Ang resolution===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3dkx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DKX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19440202}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dkx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dkx OCA], [https://pdbe.org/3dkx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dkx RCSB], [https://www.ebi.ac.uk/pdbsum/3dkx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dkx ProSAT]</span></td></tr>
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[[3dkx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKX OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/REPB_STRAG REPB_STRAG] Is essential for plasmid replication. Nicks the positive strand at the plus origin of replication.
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<ref group="xtra">PMID:019440202</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/3dkx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dkx ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptococcus agalactiae]]
[[Category: Streptococcus agalactiae]]
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[[Category: Blanco, A G.]]
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[[Category: Blanco AG]]
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[[Category: Boer, D R.]]
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[[Category: Boer DR]]
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[[Category: Coll, M.]]
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[[Category: Coll M]]
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[[Category: Espinosa, M.]]
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[[Category: Del Solar G]]
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[[Category: Gomis-Ruth, F X.]]
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[[Category: Espinosa M]]
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[[Category: Ruiz-Maso, J A.]]
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[[Category: Gomis-Ruth FX]]
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[[Category: Solar, G Del.]]
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[[Category: Ruiz-Maso JA]]
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[[Category: Uson, I.]]
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[[Category: Uson I]]
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[[Category: Vives-Llacer, M.]]
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[[Category: Vives-Llacer M]]
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[[Category: Dna replication]]
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[[Category: Flexible nuclease domain]]
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[[Category: Hexamer]]
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[[Category: Nuclease]]
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[[Category: Plasmid replication]]
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[[Category: Replication]]
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[[Category: Replication initiation]]
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[[Category: Replication initiator]]
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Current revision

Crystal Structure of the replication initiator protein encoded on plasmid pMV158 (RepB), trigonal form, to 2.7 Ang resolution

PDB ID 3dkx

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OCA

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