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1h91

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[[Image:1h91.gif|left|200px]]<br />
 
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<applet load="1h91" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1h91, resolution 1.40&Aring;" />
 
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'''THE CRYSTAL STRUCTURE OF LOBSTER APOCRUSTACYANIN A1 USING SOFTER X-RAYS.'''<br />
 
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==Overview==
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==The crystal structure of lobster apocrustacyanin A1 using softer X-rays.==
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The molecular basis of the camouflage colouration of marine crustacea is, often provided by carotenoproteins. The blue colour of the lobster, carapace, for example, is intricately associated with a, multimacromolecular 16-mer complex of protein subunits each with a bound, astaxanthin molecule. The protein subunits of crustacyanin fall into two, distinct subfamilies, CRTC and CRTA. Here, the crystal structure solution, of the A(1) protein of the CRTC subfamily is reported. The problematic, nature of the structure solution of the CRTC proteins (both C(1) and A(1)), warranted consideration and the development of new approaches. Three, putative disulfides per protein subunit were likely to exist based on, molecular-homology modelling against known lipocalin protein structures., With two such ... [[http://ispc.weizmann.ac.il/pmbin/getpm?11526313 (full description)]]
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<StructureSection load='1h91' size='340' side='right'caption='[[1h91]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1h91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homarus_gammarus Homarus gammarus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H91 FirstGlance]. <br>
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1H91 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homarus_gammarus Homarus gammarus]] with MPD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Sites: AC1, AC2, AC3 and AC4. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1H91 OCA]].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h91 OCA], [https://pdbe.org/1h91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h91 RCSB], [https://www.ebi.ac.uk/pdbsum/1h91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h91 ProSAT]</span></td></tr>
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Structure of lobster apocrustacyanin A1 using softer X-rays., Cianci M, Rizkallah PJ, Olczak A, Raftery J, Chayen NE, Zagalsky PF, Helliwell JR, Acta Crystallogr D Biol Crystallogr. 2001 Sep;57(Pt 9):1219-29. Epub 2001, Aug 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11526313 11526313]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CRA1_HOMGA CRA1_HOMGA] Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/1h91_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h91 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homarus gammarus]]
[[Category: Homarus gammarus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chayen, N.E.]]
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[[Category: Chayen NE]]
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[[Category: Cianci, M.]]
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[[Category: Cianci M]]
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[[Category: Helliwell, J.R.]]
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[[Category: Helliwell JR]]
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[[Category: Olczak, A.]]
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[[Category: Olczak A]]
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[[Category: Raftery, J.]]
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[[Category: Raftery J]]
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[[Category: Rizkallah, P.J.]]
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[[Category: Rizkallah PJ]]
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[[Category: Zagalsky, P.]]
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[[Category: Zagalsky PF]]
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[[Category: MPD]]
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[[Category: apocrustacyanin]]
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[[Category: softer x-rays]]
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[[Category: sulphurs]]
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[[Category: xenon]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 15:32:26 2007''
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Current revision

The crystal structure of lobster apocrustacyanin A1 using softer X-rays.

PDB ID 1h91

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