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3t3u

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[[Image:3t3u.png|left|200px]]
 
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{{STRUCTURE_3t3u| PDB=3t3u | SCENE= }}
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==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-130==
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<StructureSection load='3t3u' size='340' side='right'caption='[[3t3u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-130===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t3u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T3U FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22369268}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BK6:3-(6-METHOXYNAPHTHALEN-2-YL)-1-(PIPERIDIN-4-YLMETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>BK6</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3u OCA], [https://pdbe.org/3t3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t3u RCSB], [https://www.ebi.ac.uk/pdbsum/3t3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t3u ProSAT]</span></td></tr>
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[[3t3u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3U OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/Q9BJF5_TOXGO Q9BJF5_TOXGO]
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<ref group="xtra">PMID:022369268</ref><ref group="xtra">PMID:020436472</ref><ref group="xtra">PMID:021116453</ref><references group="xtra"/>
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__TOC__
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[[Category: Calcium/calmodulin-dependent protein kinase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: Larson, E T.]]
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[[Category: Larson ET]]
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[[Category: Merritt, E A.]]
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[[Category: Merritt EA]]
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[[Category: Atp-binding]]
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[[Category: Bumped kinase inhibitor]]
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[[Category: Calcium-binding]]
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[[Category: Calmodulin]]
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[[Category: Ef hand]]
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[[Category: Serine/threonine protein kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-130

PDB ID 3t3u

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