This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3eag
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3eag.png|left|200px]] | ||
| - | + | ==The crystal structure of UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (MPL) from Neisseria meningitides== | |
| - | + | <StructureSection load='3eag' size='340' side='right'caption='[[3eag]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3eag]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EAG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | == | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[3eag]] is a 2 chain structure with sequence from [ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mpl-2, mpl-1, NMB1145, NMB1183 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eag OCA], [https://pdbe.org/3eag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eag RCSB], [https://www.ebi.ac.uk/pdbsum/3eag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eag ProSAT], [https://www.topsan.org/Proteins/MCSG/3eag TOPSAN]</span></td></tr> |
| - | [[Category: Chang, C | + | </table> |
| - | [[Category: Clancy, S | + | == Evolutionary Conservation == |
| - | [[Category: Hendricks, R | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: Joachimiak, A | + | Check<jmol> |
| - | [[Category: | + | <jmolCheckbox> |
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/3eag_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eag ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Neimb]] | ||
| + | [[Category: Chang, C]] | ||
| + | [[Category: Clancy, S]] | ||
| + | [[Category: Hendricks, R]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Structural genomic]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
| - | [[Category: Midwest center for structural genomic]] | ||
[[Category: Neisseria meningitidis mc58]] | [[Category: Neisseria meningitidis mc58]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
[[Category: Udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl-meso-diaminopimelate ligase]] | [[Category: Udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl-meso-diaminopimelate ligase]] | ||
Current revision
The crystal structure of UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (MPL) from Neisseria meningitides
| |||||||||||
Categories: Large Structures | Neimb | Chang, C | Clancy, S | Hendricks, R | Joachimiak, A | Structural genomic | Atp-binding | Ligase | Mcsg | Neisseria meningitidis mc58 | Nucleotide-binding | PSI, Protein structure initiative | Udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl-meso-diaminopimelate ligase

