3eiv

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[[Image:3eiv.png|left|200px]]
 
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{{STRUCTURE_3eiv| PDB=3eiv | SCENE= }}
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==Crystal Structure of Single-stranded DNA-binding protein from Streptomyces coelicolor==
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<StructureSection load='3eiv' size='340' side='right'caption='[[3eiv]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3eiv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EIV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.141&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eiv OCA], [https://pdbe.org/3eiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eiv RCSB], [https://www.ebi.ac.uk/pdbsum/3eiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eiv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSB2_STRCO SSB2_STRCO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/3eiv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eiv ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the single-stranded DNA-binding protein (SSB) from Streptomyces coelicolor, a filamentous soil bacterium with a complex life cycle and a linear chromosome, has been solved and refined at 2.1 A resolution. The three-dimensional structure shows a common conserved central OB-fold that is found in all structurally determined SSB proteins. However, it shows variations in quaternary structure that have previously only been found in mycobacterial SSBs. The strand involved in the clamp mechanism characteristic of this type of quaternary structure leads to higher stability of the homotetramer. To the best of our knowledge, this is the first X-ray structure of an SSB protein from a member of the genus Streptomyces and it was predicted to be the most stable of the structurally characterized bacterial or human mitochondrial SSBs.
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===Crystal Structure of Single-stranded DNA-binding protein from Streptomyces coelicolor===
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Structure of the single-stranded DNA-binding protein from Streptomyces coelicolor.,Stefanic Z, Vujaklija D, Luic M Acta Crystallogr D Biol Crystallogr. 2009 Sep;65(Pt 9):974-9. Epub 2009, Aug 14. PMID:19690375<ref>PMID:19690375</ref>
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{{ABSTRACT_PUBMED_19690375}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3eiv" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[3eiv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EIV OCA].
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*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:019690375</ref><references group="xtra"/>
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__TOC__
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[[Category: Streptomyces coelicolor]]
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</StructureSection>
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[[Category: Luic, M.]]
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[[Category: Large Structures]]
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[[Category: Stefanic, Z.]]
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[[Category: Vujaklija, D.]]
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[[Category: Dna binding protein]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Dna replication]]
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[[Category: Dna-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Single-stranded dna-binding protein]]
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[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Luic M]]
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[[Category: Stefanic Z]]
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[[Category: Vujaklija D]]

Current revision

Crystal Structure of Single-stranded DNA-binding protein from Streptomyces coelicolor

PDB ID 3eiv

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