This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3dra

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3dra" [edit=sysop:move=sysop])
Current revision (09:42, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3dra.png|left|200px]]
 
-
{{STRUCTURE_3dra| PDB=3dra | SCENE= }}
+
==Candida albicans protein geranylgeranyltransferase-I complexed with GGPP==
 +
<StructureSection load='3dra' size='340' side='right'caption='[[3dra]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3dra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRA FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dra OCA], [https://pdbe.org/3dra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dra RCSB], [https://www.ebi.ac.uk/pdbsum/3dra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dra ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FNTA_CANAX FNTA_CANAX] Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dra_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dra ConSurf].
 +
<div style="clear:both"></div>
-
===Candida albicans protein geranylgeranyltransferase-I complexed with GGPP===
+
==See Also==
-
 
+
*[[Geranylgeranyl transferase 3D structures|Geranylgeranyl transferase 3D structures]]
-
{{ABSTRACT_PUBMED_18713740}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
[[3dra]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRA OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:018713740</ref><references group="xtra"/>
+
[[Category: Candida albicans]]
[[Category: Candida albicans]]
-
[[Category: Beese, L S.]]
+
[[Category: Large Structures]]
-
[[Category: Hast, M A.]]
+
[[Category: Beese LS]]
-
[[Category: Candida]]
+
[[Category: Hast MA]]
-
[[Category: Candida albican]]
+
-
[[Category: Farnesyltransferase]]
+
-
[[Category: Geranylgeranyl diphosphate]]
+
-
[[Category: Geranylgeranylpyrophosphate]]
+
-
[[Category: Geranylgeranyltransferase type-i]]
+
-
[[Category: Geranylgeranyltrasferase]]
+
-
[[Category: Ggpp]]
+
-
[[Category: Ggtase]]
+
-
[[Category: Ggtase-i]]
+
-
[[Category: Pggt]]
+
-
[[Category: Prenylation]]
+
-
[[Category: Prenyltransferase]]
+
-
[[Category: Transferase]]
+

Current revision

Candida albicans protein geranylgeranyltransferase-I complexed with GGPP

PDB ID 3dra

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3dra"
Personal tools