This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3e2q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:44, 21 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3e2q.png|left|200px]]
 
-
{{STRUCTURE_3e2q| PDB=3e2q | SCENE= }}
+
==Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with trans-4-hydroxy-L-proline==
 +
<StructureSection load='3e2q' size='340' side='right'caption='[[3e2q]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3e2q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E2Q FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e2q OCA], [https://pdbe.org/3e2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e2q RCSB], [https://www.ebi.ac.uk/pdbsum/3e2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e2q ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PUTA_ECOLI PUTA_ECOLI] Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e2q_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e2q ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with trans-4-hydroxy-L-proline===
+
==See Also==
-
 
+
*[[Proline utilization A|Proline utilization A]]
-
{{ABSTRACT_PUBMED_19140736}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Escherichia coli K-12]]
-
[[3e2q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2Q OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Tanner JJ]]
-
==Reference==
+
-
<ref group="xtra">PMID:019140736</ref><references group="xtra"/>
+
-
[[Category: Escherichia coli]]
+
-
[[Category: Proline dehydrogenase]]
+
-
[[Category: Tanner, J J.]]
+
-
[[Category: Dna-binding]]
+
-
[[Category: Fad]]
+
-
[[Category: Flavoenzyme]]
+
-
[[Category: Flavoprotein]]
+
-
[[Category: Multifunctional enzyme]]
+
-
[[Category: Nad]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Proline metabolism]]
+
-
[[Category: Proline utilization some]]
+
-
[[Category: Puta]]
+
-
[[Category: Repressor]]
+
-
[[Category: Transcription]]
+
-
[[Category: Transcription regulation]]
+

Current revision

Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with trans-4-hydroxy-L-proline

PDB ID 3e2q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools