3e9v

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[[Image:3e9v.png|left|200px]]
 
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{{STRUCTURE_3e9v| PDB=3e9v | SCENE= }}
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==Crystal structure of human B-cell Translocation Gene 2 (BTG2)==
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<StructureSection load='3e9v' size='340' side='right'caption='[[3e9v]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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===Crystal structure of human B-cell Translocation Gene 2 (BTG2)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3e9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E9V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[3e9v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9v OCA], [https://pdbe.org/3e9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e9v RCSB], [https://www.ebi.ac.uk/pdbsum/3e9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9v ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3e9v TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BTG2_HUMAN BTG2_HUMAN] Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.<ref>PMID:12771185</ref> <ref>PMID:15788397</ref> <ref>PMID:18773938</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/3e9v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e9v ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Atwell, S.]]
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[[Category: Large Structures]]
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[[Category: Burley, S K.]]
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[[Category: Atwell S]]
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[[Category: Freeman, J.]]
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[[Category: Burley SK]]
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[[Category: Hu, S.]]
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[[Category: Freeman J]]
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[[Category: Maletic, M.]]
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[[Category: Hu S]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Maletic M]]
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[[Category: Romero, R.]]
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[[Category: Romero R]]
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[[Category: Sampathkumar, P.]]
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[[Category: Sampathkumar P]]
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[[Category: Sauder, J M.]]
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[[Category: Sauder JM]]
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[[Category: Tarun, G.]]
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[[Category: Tarun G]]
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[[Category: Wasserman, S.]]
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[[Category: Wasserman S]]
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[[Category: Antiproliferative protein]]
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[[Category: B-cell translocation gene 2]]
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[[Category: Btg2]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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[[Category: Tumour supressor]]
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Current revision

Crystal structure of human B-cell Translocation Gene 2 (BTG2)

PDB ID 3e9v

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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