3e5y

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[[Image:3e5y.png|left|200px]]
 
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{{STRUCTURE_3e5y| PDB=3e5y | SCENE= }}
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==Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei==
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<StructureSection load='3e5y' size='340' side='right'caption='[[3e5y]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3e5y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei_305 Burkholderia pseudomallei 305]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E5Y FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e5y OCA], [https://pdbe.org/3e5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e5y RCSB], [https://www.ebi.ac.uk/pdbsum/3e5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e5y ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0E1SBH3_BURPE A0A0E1SBH3_BURPE] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.[HAMAP-Rule:MF_01885]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/3e5y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e5y ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei===
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==See Also==
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3e5y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei_305 Burkholderia pseudomallei 305]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E5Y OCA].
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[[Category: Burkholderia pseudomallei 305]]
[[Category: Burkholderia pseudomallei 305]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Large Structures]]
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[[Category: Decode]]
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[[Category: Methyltransferase]]
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[[Category: Protein knot]]
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[[Category: Rna methyltransferase]]
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[[Category: Seattle structural genomics center for infectious disease]]
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[[Category: Ssgcid]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei

PDB ID 3e5y

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