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3j2u
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3j2u is ON HOLD Authors: Asenjo, A.B, Chatterjee, C., Tan, D., DePaoli, V., Rice, W.J., Diaz-Avalos, R., Silvestry, M., Sosa, H. Description: Kines...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule== | |
| + | <SX load='3j2u' size='340' side='right' viewer='molstar' caption='[[3j2u]], [[Resolution|resolution]] 10.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3j2u]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. The July 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Microtubules'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_7 10.2210/rcsb_pdb/mom_2014_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J2U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2u OCA], [https://pdbe.org/3j2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j2u RCSB], [https://www.ebi.ac.uk/pdbsum/3j2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KI10A_DROME KI10A_DROME] Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux".<ref>PMID:14681690</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Kinesin 3D Structures|Kinesin 3D Structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Microtubules]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
| + | [[Category: Asenjo AB]] | ||
| + | [[Category: Chatterjee C]] | ||
| + | [[Category: DePaoli V]] | ||
| + | [[Category: Diaz-Avalos R]] | ||
| + | [[Category: Rice WJ]] | ||
| + | [[Category: Silvestry M]] | ||
| + | [[Category: Sosa H]] | ||
| + | [[Category: Tan D]] | ||
Current revision
Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule
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