4hnu
From Proteopedia
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| - | [[Image:4hnu.jpg|left|200px]] | ||
| - | + | ==crystal structure of K442E mutant of S. aureus Pyruvate carboxylase== | |
| + | <StructureSection load='4hnu' size='340' side='right'caption='[[4hnu]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4hnu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HNU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hnu OCA], [https://pdbe.org/4hnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hnu RCSB], [https://www.ebi.ac.uk/pdbsum/4hnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hnu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYC_STAAM PYC_STAAM] Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.<ref>PMID:19523900</ref> <ref>PMID:23286247</ref> | ||
| - | === | + | ==See Also== |
| - | + | *[[Pyruvate carboxylase 3D structures|Pyruvate carboxylase 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Tong | + | [[Category: Tong L]] |
| - | [[Category: Yu | + | [[Category: Yu LPC]] |
| - | + | ||
Current revision
crystal structure of K442E mutant of S. aureus Pyruvate carboxylase
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