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4dxj

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[[Image:4dxj.jpg|left|200px]]
 
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{{STRUCTURE_4dxj| PDB=4dxj | SCENE= }}
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==Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+==
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<StructureSection load='4dxj' size='340' side='right'caption='[[4dxj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dxj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DXJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0M9:[2-(PROPYLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC+ACID)'>0M9</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxj OCA], [https://pdbe.org/4dxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dxj RCSB], [https://www.ebi.ac.uk/pdbsum/4dxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q95WL3_TRYCR Q95WL3_TRYCR]
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===Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+===
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==See Also==
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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{{ABSTRACT_PUBMED_22715997}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[4dxj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXJ OCA].
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[[Category: Geranyltranstransferase]]
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Amzel, L M.]]
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[[Category: Amzel LM]]
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[[Category: Aripirala, S.]]
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[[Category: Aripirala S]]
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[[Category: Gabelli, S B.]]
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[[Category: Gabelli SB]]
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[[Category: Geranyl transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+

PDB ID 4dxj

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