1yta
From Proteopedia
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| - | [[Image:1yta.gif|left|200px]]<br /><applet load="1yta" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1yta, resolution 2.20Å" /> | ||
| - | '''Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli'''<br /> | ||
| - | == | + | ==Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli== |
| - | + | <StructureSection load='1yta' size='340' side='right'caption='[[1yta]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1yta]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YTA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yta OCA], [https://pdbe.org/1yta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yta RCSB], [https://www.ebi.ac.uk/pdbsum/1yta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yta ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | + | == Function == | |
| + | [https://www.uniprot.org/uniprot/ORN_ECOLI ORN_ECOLI] 3'-to-5' exoribonuclease specific for small oligoribonucleotides 2 to 5 nucleotides in length, as well as small (2 to 5 nucleotides) ssDNA oligomers. Probably responsible for the final step in mRNA degradation.<ref>PMID:9573169</ref> <ref>PMID:7608090</ref> <ref>PMID:16682444</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/1yta_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yta ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Exonuclease 3D structures|Exonuclease 3D structures]] | ||
| + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fiedler TJ]] | ||
| + | [[Category: Malhotra A]] | ||
| + | [[Category: Zuo Y]] | ||
Current revision
Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
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