1yur
From Proteopedia
(Difference between revisions)
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1yur.gif|left|200px]]<br /><applet load="1yur" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1yur" /> | ||
| - | '''Solution structure of apo-S100A13 (minimized mean structure)'''<br /> | ||
| - | == | + | ==Solution structure of apo-S100A13 (minimized mean structure)== |
| - | + | <StructureSection load='1yur' size='340' side='right'caption='[[1yur]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1yur]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YUR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yur OCA], [https://pdbe.org/1yur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yur RCSB], [https://www.ebi.ac.uk/pdbsum/1yur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yur ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/S10AD_HUMAN S10AD_HUMAN] Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).<ref>PMID:12746488</ref> <ref>PMID:20863990</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/1yur_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yur ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arnesano | + | [[Category: Arnesano F]] |
| - | [[Category: Banci | + | [[Category: Banci L]] |
| - | [[Category: Bertini | + | [[Category: Bertini I]] |
| - | [[Category: Fantoni | + | [[Category: Fantoni A]] |
| - | + | [[Category: Tenori L]] | |
| - | [[Category: Tenori | + | [[Category: Viezzoli MS]] |
| - | [[Category: Viezzoli | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of apo-S100A13 (minimized mean structure)
| |||||||||||
Categories: Homo sapiens | Large Structures | Arnesano F | Banci L | Bertini I | Fantoni A | Tenori L | Viezzoli MS
