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2m35
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR study of k-Ssm1a== | |
| - | + | <StructureSection load='2m35' size='340' side='right'caption='[[2m35]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2m35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Scolopendra_subspinipes Scolopendra subspinipes]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M35 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m35 OCA], [https://pdbe.org/2m35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m35 RCSB], [https://www.ebi.ac.uk/pdbsum/2m35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m35 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TX31A_SCOMU TX31A_SCOMU] This toxin inhibits voltage-gated potassium channel currents in DRG neurons (IC(50)=44.2 nM). In vivo, insects injected with this toxin showed signs of neurotoxicity including twitching, paralysis, and body contraction.<ref>PMID:22595790</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Scolopendra subspinipes]] | ||
| + | [[Category: King GF]] | ||
| + | [[Category: Lai R]] | ||
| + | [[Category: Mobli M]] | ||
| + | [[Category: Rong M]] | ||
| + | [[Category: Undheim EA]] | ||
| + | [[Category: Yang S]] | ||
Current revision
NMR study of k-Ssm1a
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Categories: Large Structures | Scolopendra subspinipes | King GF | Lai R | Mobli M | Rong M | Undheim EA | Yang S
