4iqa
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4iqa is ON HOLD Authors: Cross, M.O, Achilonu, I.A., Fernandes, M.A., Fanucchi, S., Dirr, H.W. Description: Crystal Structure Analysis of the E228L...) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure Analysis of the E228L Mutant of Human CLIC1== | |
+ | <StructureSection load='4iqa' size='340' side='right'caption='[[4iqa]], [[Resolution|resolution]] 2.49Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4iqa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IQA FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49Å</td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iqa OCA], [https://pdbe.org/4iqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iqa RCSB], [https://www.ebi.ac.uk/pdbsum/4iqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iqa ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | ||
- | + | ==See Also== | |
- | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
- | + | == References == | |
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Achilonu IA]] | ||
+ | [[Category: Cross MO]] | ||
+ | [[Category: Dirr HW]] | ||
+ | [[Category: Fanucchi S]] | ||
+ | [[Category: Fernandes MA]] |
Current revision
Crystal Structure Analysis of the E228L Mutant of Human CLIC1
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