4isz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4isz is ON HOLD Authors: Desai, K.K., Bingman, C.A., Phillips, G.N. Jr, Raines, R.T. Description: RNA ligase RtcB in complex with GTP alphaS and Mn...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==RNA ligase RtcB in complex with GTP alphaS and Mn(II)== | |
| + | <StructureSection load='4isz' size='340' side='right'caption='[[4isz]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4isz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ISZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.303Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GAV:GUANOSINE-5-RP-ALPHA-THIO-TRIPHOSPHATE'>GAV</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4isz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4isz OCA], [https://pdbe.org/4isz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4isz RCSB], [https://www.ebi.ac.uk/pdbsum/4isz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4isz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[RNA ligase|RNA ligase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pyrococcus horikoshii OT3]] | ||
| + | [[Category: Bingman CA]] | ||
| + | [[Category: Desai KK]] | ||
| + | [[Category: Phillips Jr GN]] | ||
| + | [[Category: Raines RT]] | ||
Current revision
RNA ligase RtcB in complex with GTP alphaS and Mn(II)
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