4def
From Proteopedia
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- | [[Image:4def.jpg|left|200px]] | ||
- | + | ==Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis== | |
+ | <StructureSection load='4def' size='340' side='right'caption='[[4def]], [[Resolution|resolution]] 1.64Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4def]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DEF FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4def FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4def OCA], [https://pdbe.org/4def PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4def RCSB], [https://www.ebi.ac.uk/pdbsum/4def PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4def ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ALF_MYCTU ALF_MYCTU] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity). | ||
- | == | + | ==See Also== |
- | + | *[[Aldolase 3D structures|Aldolase 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
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[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
- | [[Category: Capodagli | + | [[Category: Capodagli GC]] |
- | [[Category: Pegan | + | [[Category: Pegan SD]] |
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Current revision
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis
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