4dz0
From Proteopedia
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| - | [[Image:4dz0.jpg|left|200px]] | ||
| - | + | ==Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore== | |
| + | <StructureSection load='4dz0' size='340' side='right'caption='[[4dz0]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4dz0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DZ0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AEN:5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE'>AEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dz0 OCA], [https://pdbe.org/4dz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dz0 RCSB], [https://www.ebi.ac.uk/pdbsum/4dz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dz0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
| - | == | + | ==See Also== |
| - | + | *[[Ferritin 3D structures|Ferritin 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Huard DJE]] |
| - | [[Category: | + | [[Category: Tezcan FA]] |
| - | + | ||
Current revision
Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore
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