This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2bf3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:37, 1 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2bf3.png|left|200px]]
 
-
{{STRUCTURE_2bf3| PDB=2bf3 | SCENE= }}
+
==Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing ten N-terminal residues (delta-N10 T4moD)==
 +
<StructureSection load='2bf3' size='340' side='right'caption='[[2bf3]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2bf3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BF3 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HTO:HEPTANE-1,2,3-TRIOL'>HTO</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bf3 OCA], [https://pdbe.org/2bf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2bf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bf3 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TMOD_PSEME TMOD_PSEME] Effector protein subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol. Required for optimal efficiency and specificity of the holoenzyme.<ref>PMID:11297417</ref> <ref>PMID:15882052</ref> <ref>PMID:19033467</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/2bf3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bf3 ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF A TOLUENE 4-MONOOXYGENASE CATALYTIC EFFECTOR PROTEIN VARIANT MISSING TEN N-TERMINAL RESIDUES (DELTA-N10 T4MOD)===
+
==See Also==
-
 
+
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
-
{{ABSTRACT_PUBMED_15882052}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[2bf3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BF3 OCA].
+
</StructureSection>
-
 
+
[[Category: Large Structures]]
-
==Reference==
+
-
<ref group="xtra">PMID:015882052</ref><ref group="xtra">PMID:012595730</ref><ref group="xtra">PMID:010336868</ref><ref group="xtra">PMID:008703915</ref><references group="xtra"/>
+
[[Category: Pseudomonas mendocina]]
[[Category: Pseudomonas mendocina]]
-
[[Category: Fox, B G.]]
+
[[Category: Fox BG]]
-
[[Category: Lountos, G T.]]
+
[[Category: Lountos GT]]
-
[[Category: Mitchell, K H.]]
+
[[Category: Mitchell KH]]
-
[[Category: Orville, A M.]]
+
[[Category: Orville AM]]
-
[[Category: Studts, J M.]]
+
[[Category: Studts JM]]
-
[[Category: Aromatic hydrocarbon catabolism]]
+
-
[[Category: Catalytic effector protein]]
+
-
[[Category: Molecular replacement]]
+
-
[[Category: Monooxygenase]]
+
-
[[Category: N-terminal truncated mutant]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Toluene oxidation]]
+

Current revision

Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing ten N-terminal residues (delta-N10 T4moD)

PDB ID 2bf3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools