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2f8e

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[[Image:2f8e.png|left|200px]]
 
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{{STRUCTURE_2f8e| PDB=2f8e | SCENE= }}
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==Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein==
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<StructureSection load='2f8e' size='340' side='right'caption='[[2f8e]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2f8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot_and_mouth_disease_virus_C Foot and mouth disease virus C] and [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_Asia_1 Foot-and-mouth disease virus Asia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F8E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8e OCA], [https://pdbe.org/2f8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f8e RCSB], [https://www.ebi.ac.uk/pdbsum/2f8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f8e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q0QEE0_9PICO Q0QEE0_9PICO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/2f8e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f8e ConSurf].
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<div style="clear:both"></div>
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===Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein===
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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{{ABSTRACT_PUBMED_16456546}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Foot and mouth disease virus C]]
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[[2f8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_-_type_c Foot-and-mouth disease virus - type c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8E OCA].
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[[Category: Foot-and-mouth disease virus Asia 1]]
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[[Category: Large Structures]]
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==Reference==
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[[Category: Arias A]]
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<ref group="xtra">PMID:016456546</ref><ref group="xtra">PMID:015294895</ref><references group="xtra"/>
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[[Category: Domingo E]]
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[[Category: Foot-and-mouth disease virus - type c]]
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[[Category: Escarmis C]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Ferrer-Orta C]]
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[[Category: Arias, A.]]
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[[Category: Perez-Luque R]]
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[[Category: Domingo, E.]]
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[[Category: Verdaguer N]]
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[[Category: Escarmis, C.]]
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[[Category: Ferrer-Orta, C.]]
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[[Category: Perez-Luque, R.]]
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[[Category: Verdaguer, N.]]
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[[Category: Foot and mouth disease virus]]
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[[Category: Protein primer]]
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[[Category: Rna-dependent rna polymerase]]
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[[Category: Transferase]]
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[[Category: Vpg protein]]
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Current revision

Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein

PDB ID 2f8e

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