2dt9
From Proteopedia
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- | [[Image:2dt9.png|left|200px]] | ||
- | + | ==Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavus== | |
- | + | <StructureSection load='2dt9' size='340' side='right'caption='[[2dt9]], [[Resolution|resolution]] 2.15Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2dt9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DT9 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt9 OCA], [https://pdbe.org/2dt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2dt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dt9 ProSAT]</span></td></tr> |
- | [[2dt9]] is a 2 chain structure with sequence from [ | + | </table> |
- | + | == Function == | |
- | == | + | [https://www.uniprot.org/uniprot/AK_THETH AK_THETH] Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.<ref>PMID:7773416</ref> <ref>PMID:16232547</ref> |
- | < | + | == Evolutionary Conservation == |
- | [[Category: | + | [[Image:Consurf_key_small.gif|200px|right]] |
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dt9_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dt9 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
- | [[Category: Fushinobu | + | [[Category: Fushinobu S]] |
- | [[Category: Kuzuyama | + | [[Category: Kuzuyama T]] |
- | [[Category: Nishiyama | + | [[Category: Nishiyama M]] |
- | [[Category: Tomita | + | [[Category: Tomita T]] |
- | [[Category: Yoshida | + | [[Category: Yoshida A]] |
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- | + | ||
- | + |
Current revision
Crystal structure of the regulatory subunit of aspartate kinase from Thermus flavus
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