Fasciculin

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[[Image:1fas.png|left|200px|thumb|Crystal Structure of Fasciculin [[1fas]]]]
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<StructureSection load='' size='350' side='right' caption='Structure of Fasciculin 1 (PDB entry [[1fas]])' scene='Fasciculin/Cv/1'>
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{{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin 1 [[1fas]] }}
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[[Fasciculin|Fasciculins]] (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). For toxins in Proteopedia see [[Toxins]].
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[[Fasciculin|Fasciculins]] (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations<ref>PMID:6530667</ref> . For toxins in Proteopedia see [[Toxins]].
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</StructureSection>
== 3D Structures of Fasciculin ==
== 3D Structures of Fasciculin ==
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''Update January 2013''
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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=== Fasciculin ===
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[[1fas]] – FAS1 <br />
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[[1fsc]] - FAS2<br />
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* Fasciculin
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=== FAS+ AChE ===
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**[[1fas]] – FAS1 <br />
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**[[1fsc]] - FAS2<br />
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* FAS+ AChE
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[[2x8b]], [[1b41]], [[4ey8]] – FAS2+hAChE – human<br />
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**[[2x8b]], [[1b41]], [[4ey8]], [[4bdt]] – FAS2+hAChE – human<br />
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[[1f8u]] - FAS2+hAChE (mutant)<br />
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**[[1f8u]] - FAS2+hAChE (mutant)<br />
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[[1ku6]], [[1mah]] - FAS2+mAChE – mouse<br />
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**[[1ku6]], [[1mah]] - FAS2+mAChE – mouse<br />
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[[1fss]] - FAS2+AChE – ''Torpedo californica''<br />
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**[[1fss]] - FAS2+AChE – ''Torpedo californica''<br />
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}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of Fasciculin 1 (PDB entry 1fas)

Drag the structure with the mouse to rotate

3D Structures of Fasciculin

Updated on 20-October-2017

References

  1. ↑ Karlsson E, Mbugua PM, Rodriguez-Ithurralde D. Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps. J Physiol (Paris). 1984;79(4):232-40. PMID:6530667

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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