4b2u
From Proteopedia
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| - | [[Image:4b2u.png|left|200px]] | ||
| - | + | ==S67, A spider venom toxin peptide from Sicarius dolichocephalus== | |
| + | <StructureSection load='4b2u' size='340' side='right'caption='[[4b2u]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4b2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sicarius_dolichocephalus Sicarius dolichocephalus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B2U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b2u OCA], [https://pdbe.org/4b2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b2u RCSB], [https://www.ebi.ac.uk/pdbsum/4b2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b2u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KNO67_HEXDO KNO67_HEXDO] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | We present solution-state NMR structures for two putative venom peptides from Sicarius dolichocephalus. These peptides were identified from cDNA libraries created from venom gland mRNA and then recombinantly expressed. They are the first structures from any species of Sicarius spiders, and the first peptide structures for any haplogyne spiders. These peptides are homologous to one another, and while they have at most only 20% sequence identity with known venom peptides their structures follow the inhibitor cystine knot motif that has been found in a broad range of venom peptides. | ||
| - | + | Solution Structures of Two Homologous Venom Peptides from Sicarius dolichocephalus.,Loening NM, Wilson ZN, Zobel-Thropp PA, Binford GJ PLoS One. 2013;8(1):e54401. doi: 10.1371/journal.pone.0054401. Epub 2013 Jan 14. PMID:23342149<ref>PMID:23342149</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | == | + | <div class="pdbe-citations 4b2u" style="background-color:#fffaf0;"></div> |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Sicarius dolichocephalus]] | [[Category: Sicarius dolichocephalus]] | ||
| - | [[Category: Binford | + | [[Category: Binford GJ]] |
| - | [[Category: Loening | + | [[Category: Loening NM]] |
| - | [[Category: Wilson | + | [[Category: Wilson ZN]] |
| - | [[Category: Zobel-Thropp | + | [[Category: Zobel-Thropp PA]] |
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Current revision
S67, A spider venom toxin peptide from Sicarius dolichocephalus
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