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4dwn
From Proteopedia
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| - | [[Image:4dwn.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of Human BinCARD CARD== | |
| - | + | <StructureSection load='4dwn' size='340' side='right'caption='[[4dwn]], [[Resolution|resolution]] 1.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4dwn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DWN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.581Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[4dwn]] is a 2 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dwn OCA], [https://pdbe.org/4dwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dwn RCSB], [https://www.ebi.ac.uk/pdbsum/4dwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dwn ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAR19_HUMAN CAR19_HUMAN] Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.<ref>PMID:15637807</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chen K-E]] |
| - | [[Category: | + | [[Category: Kobe B]] |
| - | [[Category: | + | [[Category: Martin JL]] |
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Current revision
Crystal Structure of Human BinCARD CARD
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