4ddw

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[[Image:4ddw.png|left|200px]]
 
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{{STRUCTURE_4ddw| PDB=4ddw | SCENE= }}
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==Thermotoga maritima reverse gyrase, c-centered orthorhombic form==
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<StructureSection load='4ddw' size='340' side='right'caption='[[4ddw]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
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===Thermotoga maritima reverse gyrase, c-centered orthorhombic form===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ddw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DDW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_23209025}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ddw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddw OCA], [https://pdbe.org/4ddw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ddw RCSB], [https://www.ebi.ac.uk/pdbsum/4ddw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddw ProSAT]</span></td></tr>
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[[4ddw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDW OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RGYR_THEMA RGYR_THEMA] Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
==See Also==
==See Also==
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*[[Gyrase|Gyrase]]
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Klostermeier, D.]]
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[[Category: Klostermeier D]]
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[[Category: Rudolph, M G.]]
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[[Category: Rudolph MG]]
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[[Category: Archaea]]
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[[Category: Dna supercoiling]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Topoisomerase]]
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Current revision

Thermotoga maritima reverse gyrase, c-centered orthorhombic form

PDB ID 4ddw

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