3exv
From Proteopedia
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| - | [[Image:3exv.png|left|200px]] | ||
| - | + | ==Crystal structure of the human Adenovirus type 11 fiber knob== | |
| - | + | <StructureSection load='3exv' size='340' side='right'caption='[[3exv]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3exv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_mastadenovirus_B Human mastadenovirus B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exv OCA], [https://pdbe.org/3exv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exv RCSB], [https://www.ebi.ac.uk/pdbsum/3exv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exv ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3exv]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/SPIKE_ADE1P SPIKE_ADE1P] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exv_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exv ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Human mastadenovirus B]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arnberg N]] |
| - | [[Category: | + | [[Category: Persson BD]] |
| + | [[Category: Reiter DM]] | ||
| + | [[Category: Stehle T]] | ||
Current revision
Crystal structure of the human Adenovirus type 11 fiber knob
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