3exa

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[[Image:3exa.png|left|200px]]
 
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{{STRUCTURE_3exa| PDB=3exa | SCENE= }}
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==Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.==
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<StructureSection load='3exa' size='340' side='right'caption='[[3exa]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3exa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[3exa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXA OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exa OCA], [https://pdbe.org/3exa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exa RCSB], [https://www.ebi.ac.uk/pdbsum/3exa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exa ProSAT], [https://www.topsan.org/Proteins/NESGC/3exa TOPSAN]</span></td></tr>
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[[Category: Bacillus halodurans]]
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</table>
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[[Category: TRNA dimethylallyltransferase]]
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== Function ==
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[[Category: Abashidze, M.]]
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[https://www.uniprot.org/uniprot/MIAA_HALH5 MIAA_HALH5] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
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[[Category: Acton, T B.]]
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== Evolutionary Conservation ==
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[[Category: Baran, M C.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Cunningham, K.]]
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Check<jmol>
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[[Category: Forouhar, F.]]
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<jmolCheckbox>
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[[Category: Hunt, J F.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exa_consurf.spt"</scriptWhenChecked>
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[[Category: Janjua, H.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Liu, J.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Ma, L-.C.]]
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</jmolCheckbox>
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[[Category: Montelione, G T.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exa ConSurf].
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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<div style="clear:both"></div>
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[[Category: Neely, H.]]
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__TOC__
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[[Category: Rost, B.]]
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</StructureSection>
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[[Category: Seetharaman, J.]]
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[[Category: Alkalihalobacillus halodurans]]
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[[Category: Shastry, R.]]
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[[Category: Large Structures]]
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[[Category: Tong, L.]]
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[[Category: Abashidze M]]
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[[Category: Xiao, R.]]
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[[Category: Acton TB]]
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[[Category: Alpha-beta protein]]
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[[Category: Baran MC]]
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[[Category: Atp-binding]]
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[[Category: Cunningham K]]
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[[Category: Nesg]]
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[[Category: Forouhar F]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Hunt JF]]
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[[Category: Nucleotide-binding]]
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[[Category: Janjua H]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Liu J]]
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[[Category: Protein structure initiative]]
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[[Category: Ma L-C]]
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[[Category: Psi-2]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Neely H]]
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[[Category: Transferase]]
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[[Category: Rost B]]
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[[Category: Trna processing]]
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[[Category: Seetharaman J]]
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[[Category: Shastry R]]
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[[Category: Tong L]]
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[[Category: Xiao R]]

Current revision

Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.

PDB ID 3exa

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