4g0k
From Proteopedia
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| - | [[Image:4g0k.png|left|200px]] | ||
| - | + | ==Glutathionyl-hydroquinone reductase, YqjG, of E.coli complexed with GS-menadione== | |
| - | + | <StructureSection load='4g0k' size='340' side='right'caption='[[4g0k]], [[Resolution|resolution]] 2.56Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4g0k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G0K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.557Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0VS:L-GAMMA-GLUTAMYL-S-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)-L-CYSTEINYLGLYCINE'>0VS</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g0k OCA], [https://pdbe.org/4g0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g0k RCSB], [https://www.ebi.ac.uk/pdbsum/4g0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g0k ProSAT]</span></td></tr> |
| - | [[4g0k]] is a 2 chain structure with sequence from [ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/YQJG_ECOLI YQJG_ECOLI] Catalyzes glutathione (GSH)-dependent reduction of glutathionyl-hydroquinones (GS-HQs) to the corresponding hydroquinones. Can use a variety of GS-HQs as substrates, such as GS-p-hydroquinone (GS-HQ), GS-hydroxy-p-hydroquinone (GS-HHQ), GS-methyl-p-hydroquinone (GS-MHQ), GS-menadiol, and GS-trichloro-p-hydroquinone (GS-TriCH). Also displays GSH-dependent disulfide-bond reduction activity toward HED (2-hydroxyethyl disulfide), and is able to catalyze DMA (dimethylarsinate) reduction. Exhibits no GSH transferase activity with 1-chloro-2,4-dinitrobenzene (CDNB).<ref>PMID:20388120</ref> <ref>PMID:22686328</ref> <ref>PMID:22955277</ref> |
| - | [[ | + | == References == |
| - | [ | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Green AR]] | ||
| + | [[Category: Hayes RP]] | ||
| + | [[Category: Kang C]] | ||
| + | [[Category: Xun L]] | ||
Current revision
Glutathionyl-hydroquinone reductase, YqjG, of E.coli complexed with GS-menadione
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