4gcs

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[[Image:4gcs.png|left|200px]]
 
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{{STRUCTURE_4gcs| PDB=4gcs | SCENE= }}
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==Crystal Structure of E. coli OmpF porin in complex with Ertapenem==
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<StructureSection load='4gcs' size='340' side='right'caption='[[4gcs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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===Crystal Structure of E. coli OmpF porin in complex with Ertapenem===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_23201272}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1RG:(4R,5S)-3-({(3S,5S)-5-[(3-CARBOXYPHENYL)CARBAMOYL]PYRROLIDIN-3-YL}SULFANYL)-5-[(1S,2R)-1-FORMYL-2-HYDROXYPROPYL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>1RG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcs OCA], [https://pdbe.org/4gcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcs RCSB], [https://www.ebi.ac.uk/pdbsum/4gcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcs ProSAT]</span></td></tr>
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[[4gcs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCS OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>
==See Also==
==See Also==
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*[[Porin|Porin]]
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*[[Porin 3D structures|Porin 3D structures]]
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[[Category: Escherichia coli k-12]]
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== References ==
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[[Category: Roux, B.]]
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<references/>
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[[Category: Ziervogel, B K.]]
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__TOC__
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[[Category: Beta-barrel]]
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</StructureSection>
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[[Category: Ertapenem binding]]
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[[Category: Escherichia coli K-12]]
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[[Category: Membrane protein-antibiotic complex]]
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[[Category: Large Structures]]
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[[Category: Non-specific channel]]
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[[Category: Roux B]]
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[[Category: Outer membrane]]
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[[Category: Ziervogel BK]]
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[[Category: Protein-drug complex]]
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[[Category: Trimer]]
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Current revision

Crystal Structure of E. coli OmpF porin in complex with Ertapenem

PDB ID 4gcs

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