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1zy9

From Proteopedia

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[[Image:1zy9.gif|left|200px]]<br /><applet load="1zy9" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1zy9, resolution 2.340&Aring;" />
 
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'''Crystal structure of Alpha-galactosidase (EC 3.2.1.22) (Melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution'''<br />
 
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==About this Structure==
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==Crystal structure of Alpha-galactosidase (EC 3.2.1.22) (Melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution==
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1ZY9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-galactosidase Alpha-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.22 3.2.1.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZY9 OCA].
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<StructureSection load='1zy9' size='340' side='right'caption='[[1zy9]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
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[[Category: Alpha-galactosidase]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1zy9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZY9 FirstGlance]. <br>
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[[Category: Thermotoga maritima]]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zy9 OCA], [https://pdbe.org/1zy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1zy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zy9 ProSAT], [https://www.topsan.org/Proteins/JCSG/1zy9 TOPSAN]</span></td></tr>
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[[Category: EDO]]
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</table>
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[[Category: GOL]]
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== Function ==
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[[Category: alpha-galactosidase (ec 3 2.1 22) (melibiase)]]
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[https://www.uniprot.org/uniprot/AGAL_THEMA AGAL_THEMA] Hydrolyzes the short-chain alpha-galactosaccharides raffinose, melibiose and stachyose.<ref>PMID:25486100</ref> <ref>PMID:9741105</ref>
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[[Category: jcsg]]
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== Evolutionary Conservation ==
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[[Category: joint center for structural genomics]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: protein structure initiative]]
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Check<jmol>
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[[Category: psi]]
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<jmolCheckbox>
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[[Category: structural genomics]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zy9_consurf.spt"</scriptWhenChecked>
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[[Category: tm1192]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zy9 ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:14 2008''
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==See Also==
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*[[Galactosidase 3D structures|Galactosidase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermotoga maritima]]

Current revision

Crystal structure of Alpha-galactosidase (EC 3.2.1.22) (Melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution

PDB ID 1zy9

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