3f6p

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[[Image:3f6p.png|left|200px]]
 
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{{STRUCTURE_3f6p| PDB=3f6p | SCENE= }}
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==Crystal Structure of unphosphorelated receiver domain of YycF==
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<StructureSection load='3f6p' size='340' side='right'caption='[[3f6p]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3f6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F6P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f6p OCA], [https://pdbe.org/3f6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f6p RCSB], [https://www.ebi.ac.uk/pdbsum/3f6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f6p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/WALR_BACSU WALR_BACSU] Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA.<ref>PMID:10878122</ref> <ref>PMID:12950927</ref> <ref>PMID:17581128</ref> <ref>PMID:9829949</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f6p ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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YycGF is a crucial signal transduction system for the regulation of cell-wall metabolism in low-G+C Gram-positive bacteria, which include many important human pathogens. The response regulator YycF receives signals from its cognate histidine kinase YycG through a phosphotransfer reaction and elicits responses through regulation of gene expression. The N-terminal regulatory domain of YycF from Bacillus subtilis was overproduced and purified. The protein was crystallized and X-ray data were collected to 1.95 A resolution with a completeness of 97.7% and an overall R(merge) of 7.7%. The crystals belonged to space group P3(1)21, with unit-cell parameters a = b = 59.50, c = 79.06 A.
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===Crystal Structure of unphosphorelated receiver domain of YycF===
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Preliminary crystallographic studies of the regulatory domain of response regulator YycF from an essential two-component signal transduction system.,Zhao H, Heroux A, Sequeira RD, Tang L Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt, 7):719-22. Epub 2009 Jun 27. PMID:19574649<ref>PMID:19574649</ref>
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{{ABSTRACT_PUBMED_19574649}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 3f6p" style="background-color:#fffaf0;"></div>
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[[3f6p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6P OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:019574649</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Bacillus subtilis]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Tang, L.]]
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[[Category: Large Structures]]
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[[Category: Zhao, H.]]
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[[Category: Tang L]]
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[[Category: Dna binding protein]]
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[[Category: Zhao H]]
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[[Category: Dna-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Receiver domain]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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[[Category: Two-component regulatory system]]
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[[Category: Unphosphorelated]]
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Current revision

Crystal Structure of unphosphorelated receiver domain of YycF

PDB ID 3f6p

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