2a10

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[[Image:2a10.gif|left|200px]]<br /><applet load="2a10" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2a10, resolution 1.803&Aring;" />
 
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'''carboxysome shell protein ccmK4'''<br />
 
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==Overview==
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==carboxysome shell protein ccmK4==
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Bacterial microcompartments are primitive organelles composed entirely of protein subunits. Genomic sequence databases reveal the widespread occurrence of microcompartments across diverse microbes. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. We report three-dimensional crystal structures of multiple carboxysome shell proteins, revealing a hexameric unit as the basic microcompartment building block and showing how these hexamers assemble to form flat facets of the polyhedral shell. The structures suggest how molecular transport across the shell may be controlled and how structural variations might govern the assembly and architecture of these subcellular compartments.
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<StructureSection load='2a10' size='340' side='right'caption='[[2a10]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2a10]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803 Synechocystis sp. PCC 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A10 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.803&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a10 OCA], [https://pdbe.org/2a10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a10 RCSB], [https://www.ebi.ac.uk/pdbsum/2a10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a10 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CCMK4_SYNY3 CCMK4_SYNY3] May be involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a10_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a10 ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2A10 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A10 OCA].
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Protein structures forming the shell of primitive bacterial organelles., Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO, Science. 2005 Aug 5;309(5736):936-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16081736 16081736]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Synechocystis sp. PCC 6803]]
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[[Category: Synechocystis sp.]]
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[[Category: Beeby M]]
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[[Category: Beeby, M.]]
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[[Category: Kerfeld CA]]
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[[Category: Kerfeld, C A.]]
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[[Category: Nguyen CV]]
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[[Category: Nguyen, C V.]]
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[[Category: Phillips M]]
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[[Category: Phillips, M.]]
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[[Category: Sawaya MR]]
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[[Category: Sawaya, M R.]]
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[[Category: Tanaka S]]
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[[Category: Tanaka, S.]]
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[[Category: Yeates TO]]
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[[Category: Yeates, T O.]]
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[[Category: cyclic hexamer; c6 point symmetry]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:22:32 2008''
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Current revision

carboxysome shell protein ccmK4

PDB ID 2a10

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