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2a3s
From Proteopedia
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| - | [[Image:2a3s.gif|left|200px]]<br /><applet load="2a3s" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2a3s" /> | ||
| - | '''Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor'''<br /> | ||
| - | == | + | ==Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor== |
| - | + | <StructureSection load='2a3s' size='340' side='right'caption='[[2a3s]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[2a3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A3S FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a3s OCA], [https://pdbe.org/2a3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a3s RCSB], [https://www.ebi.ac.uk/pdbsum/2a3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a3s ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/FOXK1_MOUSE FOXK1_MOUSE] Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.<ref>PMID:8007964</ref> <ref>PMID:9271401</ref> |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/2a3s_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a3s ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[FOX 3D structures|FOX 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Chang C-H]] | ||
| + | [[Category: Chu Y-P]] | ||
| + | [[Category: Chuang W-J]] | ||
| + | [[Category: Jeng W-Y]] | ||
Current revision
Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor
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