4j7q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4j7q is ON HOLD Authors: Yang, H., Im, Y.J. Description: Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol== | |
| - | + | <StructureSection load='4j7q' size='340' side='right'caption='[[4j7q]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4j7q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J7Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B7N:(1R)-2-{[(S)-HYDROXY{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL]OXY}-1-[(OCTADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>B7N</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j7q OCA], [https://pdbe.org/4j7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j7q RCSB], [https://www.ebi.ac.uk/pdbsum/4j7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j7q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDR16_YEAST PDR16_YEAST] Has phosphatidylinositol transfer activity. Involved in the regulation of the phospholipid composition of plasma- and endomembranes. Altering plasma membrane composition may provide a possible mechanism for multidrug resistance. Involved in the regulation of sterol biosynthesis. Contributes to efficient phospholipase D1 activation in the regulation of phospholipid turnover.<ref>PMID:9890948</ref> <ref>PMID:10848624</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Im YJ]] | ||
| + | [[Category: Yang H]] | ||
Current revision
Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol
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