4dof
From Proteopedia
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| - | [[Image:4dof.jpg|left|200px]] | ||
| - | + | ==Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms== | |
| + | <StructureSection load='4dof' size='340' side='right'caption='[[4dof]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4dof]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DOF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dof OCA], [https://pdbe.org/4dof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dof RCSB], [https://www.ebi.ac.uk/pdbsum/4dof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dof ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). | ||
| - | == | + | ==See Also== |
| - | + | *[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Vaccinia virus Western Reserve]] |
| - | [[Category: Vaccinia virus | + | [[Category: Chattopadhyay D]] |
| - | [[Category: Chattopadhyay | + | [[Category: Schormann N]] |
| - | [[Category: Schormann | + | |
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Current revision
Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms
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