4dpr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:41, 14 March 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4dpr.jpg|left|200px]]
 
-
{{STRUCTURE_4dpr| PDB=4dpr | SCENE= }}
+
==Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril==
 +
<StructureSection load='4dpr' size='340' side='right'caption='[[4dpr]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4dpr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DPR FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dpr OCA], [https://pdbe.org/4dpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dpr RCSB], [https://www.ebi.ac.uk/pdbsum/4dpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dpr ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/LKHA4_HUMAN LKHA4_HUMAN] Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:1975494</ref> <ref>PMID:2244921</ref> <ref>PMID:12207002</ref> <ref>PMID:11917124</ref> <ref>PMID:15078870</ref> <ref>PMID:18804029</ref>
-
===Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril===
+
==See Also==
-
 
+
*[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[4dpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPR OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Haeggstrom, J Z.]]
+
[[Category: Large Structures]]
-
[[Category: Rinaldo-Matthis, A.]]
+
[[Category: Haeggstrom JZ]]
-
[[Category: Stsiapanava, A.]]
+
[[Category: Rinaldo-Matthis A]]
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
[[Category: Stsiapanava A]]
-
[[Category: Leukotriene a4]]
+
-
[[Category: Metalloprotein]]
+
-
[[Category: Protease]]
+
-
[[Category: Zinc binding]]
+

Current revision

Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril

PDB ID 4dpr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4dpr"
Personal tools