4il2

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[[Image:4il2.jpg|left|200px]]
 
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{{STRUCTURE_4il2| PDB=4il2 | SCENE= }}
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==Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)==
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<StructureSection load='4il2' size='340' side='right'caption='[[4il2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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===Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4il2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IL2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[4il2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_cft073 Escherichia coli cft073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL2 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4il2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4il2 OCA], [https://pdbe.org/4il2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4il2 RCSB], [https://www.ebi.ac.uk/pdbsum/4il2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4il2 ProSAT]</span></td></tr>
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[[Category: Escherichia coli cft073]]
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</table>
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[[Category: Gerlt, J A.]]
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== Function ==
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[[Category: Imker, H J.]]
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[https://www.uniprot.org/uniprot/MAND_ECOL6 MAND_ECOL6] Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
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[[Category: Lukk, T.]]
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== References ==
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[[Category: Nair, S K.]]
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<references/>
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[[Category: Wichelecki, D.]]
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__TOC__
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[[Category: Lyase]]
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</StructureSection>
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[[Category: Tim-barrel]]
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[[Category: Escherichia coli CFT073]]
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[[Category: Large Structures]]
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[[Category: Gerlt JA]]
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[[Category: Imker HJ]]
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[[Category: Lukk T]]
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[[Category: Nair SK]]
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[[Category: Wichelecki D]]

Current revision

Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)

PDB ID 4il2

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