3fuu

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[[Image:3fuu.png|left|200px]]
 
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{{STRUCTURE_3fuu| PDB=3fuu | SCENE= }}
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==T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with Adenosine in space group P212121==
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<StructureSection load='3fuu' size='340' side='right'caption='[[3fuu]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3fuu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FUU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fuu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fuu OCA], [https://pdbe.org/3fuu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fuu RCSB], [https://www.ebi.ac.uk/pdbsum/3fuu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fuu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RSMA_THET8 RSMA_THET8] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.[HAMAP-Rule:MF_00607]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/3fuu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fuu ConSurf].
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<div style="clear:both"></div>
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===T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with Adenosine in space group P212121===
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==See Also==
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*[[Adenosine dimethyltransferase 3D structures|Adenosine dimethyltransferase 3D structures]]
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{{ABSTRACT_PUBMED_19285505}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3fuu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FUU OCA].
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[[Category: Thermus thermophilus HB8]]
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[[Category: Belardinelli R]]
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==Reference==
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[[Category: Dahlberg AE]]
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<ref group="xtra">PMID:019285505</ref><references group="xtra"/>
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[[Category: Demirci H]]
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[[Category: Thermus thermophilus]]
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[[Category: Gregory ST]]
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[[Category: Belardinelli, R.]]
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[[Category: Gualerzi C]]
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[[Category: Dahlberg, A E.]]
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[[Category: Jogl G]]
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[[Category: Demirci, H.]]
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[[Category: Seri E]]
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[[Category: Gregory, S T.]]
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[[Category: Gualerzi, C.]]
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[[Category: Jogl, G.]]
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[[Category: Seri, E.]]
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[[Category: 16s rrna methyltransferase]]
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[[Category: Antibiotic resistance]]
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[[Category: Dimethyltransferase]]
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[[Category: Dual-specific methyltransferase]]
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[[Category: Methyltransferase]]
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[[Category: Rna-binding]]
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[[Category: Rrna processing]]
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[[Category: S-adenosyl-l-methionine]]
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[[Category: Transferase]]
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[[Category: Translation]]
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Current revision

T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with Adenosine in space group P212121

PDB ID 3fuu

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